Primary intracranial yolk sac tumor in the posterior fossa: case report of a child with Down syndrome.

Down syndrome (DS) has an increased risk of leukemia and a ecreased incidence of solid tumors [1]. However, Asian patients ith DS do not have a lower risk of brain tumors, especially germ ell tumors [2]. Satge et al. summarized 38 central nervous system umors in DS and reported that 14 (61%) of 23 cases under age 5 were germ cell tumors [3]. All reported cases were Asian, and olk sac tumors (YST) had the highest occurrence. Recently, the ssociation between germ cell tumors and DS has been reported. e report a case of intracranial YST originating from the posterior ossa dura mater. Although DS related intracranial GCTs tend to ccur in atypical sites such as the basal ganglia, origination in the osterior fossa dura is extremely rare.